Description

(5R)-6,7-Dihydro-2-Phenyl-5-(Phenylmethyl)-5H-Pyrrolo[2,1-C]-1,2,4-Triazolium Tetrafluoroborate is a high-purity, non-racemic chiral ionic liquid and a key synthetic intermediate. Its value lies in its role as a specialized building block for the development of novel pharmaceuticals, advanced materials, and chiral catalysts. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to incorporate its unique fused triazolium-pyrrole structure into complex molecules.

Application

• Pharmaceutical Intermediate: A critical chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective drug candidates.
• Asymmetric Catalysis: Serves as a precursor for designing novel chiral N-heterocyclic carbene (NHC) ligands and organocatalysts for stereoselective transformations.
• Advanced Material Synthesis: Used in the research and development of ionic liquid crystals, conductive polymers, and other functional organic materials.
• Agrochemical Research: Employed as a building block for creating new generations of chiral herbicides, fungicides, and plant growth regulators.
• Academic & Industrial R&D: A valuable tool for method development and exploring new reaction pathways in organic and medicinal chemistry.

Basic Information

Product Name	(5R)-6,7-Dihydro-2-Phenyl-5-(Phenylmethyl)-5H-Pyrrolo[2,1-C]-1,2,4-Triazolium Tetrafluoroborate
CAS No.	463326-92-3
Molecular Formula	C19H18BF4N3
Molecular Weight	367.17 g/mol
Synonyms	(5R)-5-Benzyl-2-phenyl-5,6,7-trihydro-4H-pyrrolo[2,1-c][1,2,4]triazol-4-ium tetrafluoroborate; (R)-5-Benzyl-2-phenyl-5,6-dihydro-4H-pyrrolo[2,1-c][1,2,4]triazol-4-ium tetrafluoroborate; (5R)-5-Benzyl-2-phenyl-4,5,6,7-tetrahydro-2H-pyrrolo[2,1-c][1,2,4]triazol-4-ium tetrafluoroborate; (R)-5-Benzyl-2-phenyl-5,6,7-trihydro-4H-pyrrolo[2,1-c][1,2,4]triazol-4-ium tetrafluoroborate(1-); Chiral Triazolium Salt; (R)-Triazolium Tetrafluoroborate
EINECS	Contact for details

Quality Control

Our (5R)-6,7-Dihydro-2-Phenyl-5-(Phenylmethyl)-5H-Pyrrolo[2,1-C]-1,2,4-Triazolium Tetrafluoroborate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and chiral excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.