Description

1-Azabicyclo[2.2.2]Octane-4-Methanol, α,α-Diphenyl- is a sophisticated bicyclic tertiary amine derivative, serving as a key chiral building block and ligand in advanced organic synthesis. This compound matters for its unique structural framework, which is highly valuable in the development of pharmaceuticals and fine chemicals, particularly for creating molecules with specific three-dimensional architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in catalysis and as a precursor to active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical chiral building block in the synthesis of complex drug molecules, particularly those targeting the central nervous system.
• Catalyst Ligand: Used in asymmetric synthesis as a ligand for metal catalysts to induce chirality in reaction products.
• Agrochemical Research: Serves as a precursor in the development of novel pesticides and herbicides with specific activity profiles.
• Academic & R&D: Employed in university and institutional research for methodological studies in organic and medicinal chemistry.
• Fine Chemical Synthesis: Utilized in the production of specialty chemicals, flavors, and fragrances requiring precise stereochemical control.
• Material Science: Investigated as a monomer or additive for creating polymers with specific functional properties.

Basic Information

Product Name	1-Azabicyclo[2.2.2]Octane-4-Methanol, α,α-Diphenyl-
CAS No.	461648-39-5
Molecular Formula	C20H23NO
Molecular Weight	293.41 g/mol
Synonyms	4-(Diphenylhydroxymethyl)-1-azabicyclo[2.2.2]octane; α,α-Diphenyl-1-azabicyclo[2.2.2]octane-4-methanol; 1-Azabicyclo[2.2.2]octan-4-yl(diphenyl)methanol; 4-(Hydroxy(diphenyl)methyl)-1-azabicyclo[2.2.2]octane; Quinuclidin-4-yl(diphenyl)methanol; DPCQ; Aza-Bicyclic Tertiary Alcohol
EINECS	Contact for details

Quality Control

Our 1-Azabicyclo[2.2.2]Octane-4-Methanol, α,α-Diphenyl- is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.