Description

1-[4-(5,5-Dimethyl-1,3,2-Dioxaborinan-2-Yl)Phenyl]Ethan-1-One is a high-purity, advanced pharmaceutical intermediate featuring a protected boronic ester functional group. This compound is a critical building block in modern synthetic organic chemistry, enabling precise carbon-carbon bond formation under mild conditions. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for constructing biaryl and heterobiaryl structures in drug discovery and material science.
• Pharmaceutical Intermediate: Serves as a versatile precursor in the synthesis of complex molecules targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and herbicides.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors.
• Chemical Biology Probes: Acts as a building block for creating molecular probes and diagnostic tools.
• Process Chemistry Development: Utilized in scaling up synthetic routes from laboratory to pilot and commercial production.

Basic Information

Product Name	1-[4-(5,5-Dimethyl-1,3,2-Dioxaborinan-2-Yl)Phenyl]Ethan-1-One
CAS No.	460088-33-9
Molecular Formula	C14H19BO3
Molecular Weight	246.11 g/mol
Synonyms	4-Acetylphenylboronic acid pinacol ester; 1-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]ethanone; 4-Acetylbenzeneboronic acid pinacol ester; 4-Acetylphenylboronic acid neopentyl glycol ester; 2-[4-Acetylphenyl]-5,5-dimethyl-1,3,2-dioxaborinane; 4-Acetylphenyl-Bpin; 4-Acetylbenzeneboronic acid cyclic ester; 4-Acetylphenylboronate pinacol ester
EINECS	Contact for details

Quality Control

Our 1-[4-(5,5-Dimethyl-1,3,2-Dioxaborinan-2-Yl)Phenyl]Ethan-1-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged use or when opening the primary container to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.