Description

2-Phenylthiophene-5-Boronic Acid Pinacol Ester is a high-purity organoboron reagent, specifically a boronic ester derivative, widely utilized as a key synthetic building block in cross-coupling reactions. Its primary value lies in enabling the efficient and selective formation of carbon-carbon bonds, which is fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly in the development of active pharmaceutical ingredients (APIs), organic electronic materials, and novel chemical entities.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A critical reagent for constructing biaryl and heterobiaryl systems in medicinal chemistry and material science.
• Pharmaceutical Intermediate: Serves as a versatile building block in the synthesis of potential drug candidates, especially those containing thiophene and phenyl motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Organic Light-Emitting Diodes (OLEDs): A precursor for creating electron-transport or emissive layer materials in display and lighting technologies.
• Polymer and Material Science: Employed to synthesize conjugated polymers and organic semiconductors for electronic devices.
• Chemical Research & Development: A valuable tool for academic and industrial R&D labs exploring new synthetic methodologies and compound libraries.

Basic Information

Product Name	2-Phenylthiophene-5-Boronic Acid Pinacol Ester
CAS No.	459409-74-6
Molecular Formula	C16H19BO2S
Molecular Weight	286.20 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-phenylthiophene; 2-Phenyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene; (2-Phenylthiophen-5-yl)boronic acid pinacol ester; 2-Phenyl-5-(pinacolboryl)thiophene; 5-Pinacolatoboryl-2-phenylthiophene; 2-Phenylthien-5-ylboronic acid pinacol ester; 459409-74-6
EINECS	Contact for details

Quality Control

Every batch of 2-Phenylthiophene-5-Boronic Acid Pinacol Ester undergoes rigorous analytical testing to ensure it meets the high-purity standards required for sensitive cross-coupling applications. Our quality assurance protocol includes advanced chromatographic and spectroscopic methods to verify identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.