Description

3-Bromo-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine is a high-value, organoboron building block essential for modern synthetic chemistry. This compound serves as a critical intermediate in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: Key building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides requiring complex pyridine derivatives.
• Material Science Research: Employed in the creation of organic electronic materials, such as ligands for OLEDs and conductive polymers.
• Chemical Biology & Proteomics: Serves as a versatile handle for bioconjugation and the synthesis of molecular probes and inhibitors.
• Academic & Industrial R&D: Fundamental reagent for methodological development in organic synthesis and catalysis studies.
• Fine Chemical Production: Intermediate for manufacturing specialty chemicals with specific functionalization on the pyridine ring.

Basic Information

Product Name	3-Bromo-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
CAS No.	458532-92-8
Molecular Formula	C11H15BBrNO2
Molecular Weight	284.0 g/mol
Synonyms	3-Bromo-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-(3-Bromopyridin-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-Bromo-4-pyridineboronic acid pinacol ester; 3-Bromo-4-(pinacolboryl)pyridine; 4,4,5,5-Tetramethyl-2-(3-bromo-4-pyridinyl)-1,3,2-dioxaborolane; 3-Bromo-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 3-Bromo-4-(pinacolatoboryl)pyridine; 3-Bromo-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)pyridine
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing batch-specific results are provided to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.