Description

3-Fluoro-4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)Pyridine is a high-value organoboron building block, specifically a pyridine-substituted pinacol boronic ester. This compound is critical for modern synthetic chemistry, enabling efficient carbon-carbon bond formation through cross-coupling reactions. It is primarily utilized by research scientists and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing fluorinated pyridine derivatives with potential biological activity.
• Agrochemical Synthesis: Used in the research and development of new crop protection agents and herbicides that incorporate the fluoropyridine moiety.
• Ligand and Catalyst Development: Serves as a building block for creating novel ligands and complex organic frameworks used in catalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as those for OLEDs or semiconductors, where the boronic ester group facilitates polymerization or functionalization.
• Chemical Biology Probes: Useful for labeling and modifying biomolecules in drug discovery and diagnostic assay development.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds for client R&D pipelines.

Basic Information

Product Name	3-Fluoro-4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)Pyridine
CAS No.	458532-88-2
Molecular Formula	C11H15BFNO2
Molecular Weight	223.05 g/mol
Synonyms	3-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-fluoropyridine; 3-Fluoro-4-pyridineboronic acid pinacol ester; 3-Fluoro-4-(pinacolboryl)pyridine; 3-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin; 3-Fluoro-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
EINECS	Contact for details

Quality Control

Our production of 3-Fluoro-4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)Pyridine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. All materials are fully characterized and tested. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.