Description

2-Chloropyridine-4-Boronic Acid Pinacol Ester is a high-value, organoboron building block essential for modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecules. This compound is critically needed by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for constructing pyridine-based scaffolds in drug discovery and development, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific chloropyridine motifs.
• Material Science: Serves as a precursor for creating functionalized polymers, liquid crystals, and organic electronic materials through cross-coupling polymerization.
• Chemical Research & Development: An indispensable reagent in academic and industrial R&D labs for methodology development and library synthesis.
• Ligand Synthesis: Employed in the preparation of sophisticated bidentate or tridentate ligands for catalysis and coordination chemistry.

Basic Information

Product Name	2-Chloropyridine-4-Boronic Acid Pinacol Ester
CAS No.	458532-84-8
Molecular Formula	C11H15BClNO2
Molecular Weight	239.51 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-chloropyridine; 2-Chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-Chloro-4-pyridineboronic acid pinacol ester; (2-Chloropyridin-4-yl)boronic acid pinacol ester; 2-Chloro-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-Chloro-4-pyridylboronic acid pinacol ester; 2-Chloro-4-boronopyridine pinacol ester
EINECS	Contact for details

Quality Control

Our 2-Chloropyridine-4-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR (1H, 13C, 11B), and GC/MS, to ensure high purity and consistency. Certificates of Analysis (COA) with full analytical data are provided to guarantee compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term stability, as boronic esters can be moisture-sensitive.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.