Description

4-Hydroxy-trans-β-Styrylboronic Acid Pinacol Ester is a high-purity, advanced boronic ester building block used in modern synthetic chemistry. This compound is valued for its stability and reactivity, serving as a crucial intermediate in cross-coupling reactions to construct complex molecular architectures. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for creating novel active ingredients and functional materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of complex biaryl and styryl derivatives.
• Pharmaceutical Intermediate: Used in the research and development of new drug candidates, particularly those containing a hydroxystilbene or related scaffold.
• Agrochemical Synthesis: Employed in creating novel active ingredients for crop protection products.
• Materials Science Research: Serves as a building block for organic electronic materials, such as OLEDs and semiconductors.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying biological processes.
• Academic & Industrial R&D: A versatile tool for methodological development and library synthesis in discovery chemistry.

Basic Information

Product Name	4-Hydroxy-trans-β-Styrylboronic Acid Pinacol Ester
CAS No.	457957-24-3
Molecular Formula	C16H23BO3
Molecular Weight	274.17 g/mol
Synonyms	trans-4-Hydroxystyrylboronic Acid Pinacol Ester; (E)-4-(2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)vinyl)phenol; 4-Hydroxy-trans-styrylboronic Acid Pinacol Ester; 4-Hydroxy-(E)-styrylboronic Acid Pinacol Ester; Pinacol (E)-4-(2-Boronovinyl)phenyl Ester; 457957-24-3; 4-Hydroxy-trans-β-styrylboronic Acid Pinacol Ester
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-trans-β-Styrylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high chemical purity and isomeric integrity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Isomeric Purity (trans-)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.