Description

1-Methyl-1,2,3,6-Tetrahydropyridine-4-Boronic Acid Pinacol Ester is a versatile and highly valuable organoboron building block used in advanced organic synthesis. Its core value proposition lies in its stability and reactivity as a key intermediate in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and material science industries, particularly for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in CNS (Central Nervous System) and other therapeutic areas.
• Agrochemical Synthesis: Used to create complex heterocyclic structures found in advanced pesticides, herbicides, and fungicides.
• Material Science Research: Serves as a building block for developing organic electronic materials, such as OLED (Organic Light-Emitting Diode) components and conductive polymers.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and activity-based protein profiling (ABPP) reagents due to its boronic ester functionality.
• Catalyst & Ligand Development: Acts as a precursor for synthesizing novel ligands and catalysts used in asymmetric synthesis and other catalytic processes.
• Academic & R&D Laboratories: A fundamental reagent for methodological development in organic chemistry and for exploring new synthetic pathways.

Basic Information

Item	Details
Product Name	1-Methyl-1,2,3,6-Tetrahydropyridine-4-Boronic Acid Pinacol Ester
CAS No.	454482-11-2
Molecular Formula	C12H22BNO2
Molecular Weight	223.12 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-methyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2,3,6-tetrahydropyridine; 1-Methyl-1,2,3,6-tetrahydro-4-pyridineboronic acid pinacol ester; 1-Methyl-4-(pinacolboryl)-1,2,3,6-tetrahydropyridine; 1-Methyl-1,2,3,6-tetrahydropyridin-4-ylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 1-Methyl-1,2,3,6-Tetrahydropyridine-4-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95% (Typical 97-99%)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.