Description

(4-Methoxycarbonylmethylphenyl)Boronic Acid Pinacol Ester is a high-purity boronic ester derivative, a crucial protected intermediate in modern synthetic chemistry. Its primary value lies in enabling efficient and selective Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality building blocks for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key protected building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific biphenyl motifs.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the construction of organic electronic materials, such as those for OLEDs and organic photovoltaics, where precise molecular architecture is critical.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological processes and target engagement.
• Custom Fine Chemical Manufacturing: An important reagent for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Item	Details
Product Name	(4-Methoxycarbonylmethylphenyl)Boronic Acid Pinacol Ester
CAS No.	454185-98-9
Molecular Formula	C16H23BO4
Molecular Weight	290.16 g/mol
Synonyms	4-(Methoxycarbonylmethyl)benzeneboronic acid pinacol ester; Methyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenylacetate; [4-(Methoxycarbonylmethyl)phenyl]boronic acid pinacol ester; 4-(Pinacolboryl)phenylacetic acid methyl ester; Methyl [4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]acetate; Boronic acid, B-[4-(methoxycarbonylmethyl)phenyl]-, pinacol ester
EINECS	Contact for details

Quality Control

Every batch of (4-Methoxycarbonylmethylphenyl)Boronic Acid Pinacol Ester is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure consistency and high purity. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from NMR (1H, 13C, 11B), HPLC, and other relevant techniques. Our quality commitment aligns with the standards expected for fine chemical and pharmaceutical-grade intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.