Description

1-Bromo-3-Fluoro-5-Methylsulfanylbenzene is a high-purity halogenated aromatic building block essential for advanced organic synthesis. Its unique structure, featuring bromine, fluorine, and a methylthio group, makes it a versatile intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in Suzuki-Miyaura and other cross-coupling reactions to introduce complex aryl groups.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine and sulfur motifs can enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalization agent in the synthesis of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new reaction pathways, creating ligand libraries for catalysis, and developing novel chemical entities.
• Dye and Pigment Intermediate: Acts as a building block for synthesizing specialized dyes and pigments where halogen and sulfur substituents modify color and fastness properties.

Basic Information

Product Name	1-Bromo-3-Fluoro-5-Methylsulfanylbenzene
CAS No.	453566-03-5
Molecular Formula	C7H6BrFS
Molecular Weight	221.09 g/mol
Synonyms	3-Bromo-5-Fluorophenyl Methyl Sulfide; 5-Bromo-3-Fluorophenyl Methyl Sulfide; 1-Bromo-3-Fluoro-5-(Methylthio)benzene; Benzene, 1-bromo-3-fluoro-5-(methylthio)-; 3-Fluoro-5-bromothioanisole; Methyl 3-bromo-5-fluorophenyl sulfide
EINECS	Contact for details

Quality Control

Our 1-Bromo-3-Fluoro-5-Methylsulfanylbenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, assay, and impurity profiles. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliability for your critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.