Description

2-Bromo-3-Pyridineboronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex heterocyclic scaffolds. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key reagent in Suzuki-Miyaura cross-coupling reactions for the synthesis of novel, biologically active pyridine-containing compounds.
• Agrochemical Research: Used to create advanced pyridine-based ligands and active ingredients for crop protection products.
• Material Science: Employed in the development of organic electronic materials, such as OLEDs and conductive polymers, where specific pyridine architectures are required.
• Chemical Biology: Facilitates the synthesis of molecular probes and tool compounds for target identification and validation in biological systems.
• Catalyst & Ligand Development: Acts as a precursor for creating specialized ligands used in homogeneous catalysis.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Bromo-3-Pyridineboronic Acid Pinacol Ester
CAS No.	452972-12-2
Molecular Formula	C11H15BBrNO2
Molecular Weight	268.96 g/mol
Synonyms	2-Bromo-3-pyridinylboronic acid pinacol ester; (2-Bromopyridin-3-yl)boronic acid pinacol ester; 2-Bromo-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 3-Bromo-2-pyridineboronic acid pinacol ester; Pinacol (2-bromopyridin-3-yl)boronate; 452972-12-2; BRN 8510035
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-Pyridineboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and support your regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. The product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.