Description

4-[2-(4-Bromo-2-Fluorophenoxy)Phenyl]-3-Buten-2-One is a high-purity, advanced pharmaceutical intermediate characterized by its specific halogenated aromatic structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and inflammatory pathways. It is primarily required by R&D laboratories and production facilities in the pharmaceutical and agrochemical sectors for developing new therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in neurological and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides due to its halogenated phenoxy moiety.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a precursor for electron-transport or host materials in electronic applications.
• Liquid Crystal & Polymer Chemistry: Acts as a monomer or cross-linking agent for creating specialty polymers with specific optical properties.
• Academic & Industrial R&D: Essential for methodological studies in organic synthesis, particularly cross-coupling and condensation reactions.
• Fine Chemical Production: Employed in the manufacture of complex fragrance and dye intermediates.

Basic Information

Product Name	4-[2-(4-Bromo-2-Fluorophenoxy)Phenyl]-3-Buten-2-One
CAS No.	451485-72-6
Molecular Formula	C₁₆H₁₂BrFO₂
Molecular Weight	335.17 g/mol
Synonyms	4-[2-(4-Bromo-2-fluorophenoxy)phenyl]but-3-en-2-one; (E)-4-[2-(4-Bromo-2-fluorophenoxy)phenyl]but-3-en-2-one; 1-[2-[(4-Bromo-2-fluorophenyl)oxy]phenyl]-3-buten-2-one; 4-(2-(4-Bromo-2-fluorophenoxy)phenyl)-3-buten-2-one; 4-(2-(4-Bromo-2-fluorophenoxy)phenyl)but-3-en-2-one; CAS 451485-72-6
EINECS	Contact for details

Quality Control

Our 4-[2-(4-Bromo-2-Fluorophenoxy)Phenyl]-3-Buten-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our production adheres to cGMP guidelines where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.