Description

Methyl 4-(2-Chlorophenyl)-2,4-Dioxobutanoate is a high-purity organic intermediate characterized by its β-keto ester functionality and chlorinated aromatic ring. This compound is valued for its role as a versatile building block in the synthesis of complex heterocyclic and pharmaceutical molecules. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those with chlorophenyl motifs, for therapeutic areas such as CNS disorders and anti-infectives.
• Agrochemical Synthesis: Serves as a critical building block for developing novel herbicides, fungicides, and insecticides, leveraging its reactive dioxobutanoate core.
• Fine Chemical Production: Used in the manufacture of specialty chemicals, dyes, and complex organic compounds requiring precise molecular architecture.
• Academic & Industrial R&D: Essential material for method development, catalysis studies, and exploring new chemical reactions in process chemistry.
• Material Science Research: Investigated as a monomer or cross-linking agent for creating polymers with specific optical or electronic properties.

Basic Information

Item	Detail
Product Name	Methyl 4-(2-Chlorophenyl)-2,4-Dioxobutanoate
CAS No.	451485-68-0
Molecular Formula	C11H9ClO4
Molecular Weight	240.64 g/mol
Synonyms	Methyl 2-chlorobenzoylpyruvate; 4-(2-Chlorophenyl)-2,4-dioxobutanoic Acid Methyl Ester; 2-Chlorobenzoylpyruvic Acid Methyl Ester; Methyl (2-Chlorobenzoyl)pyruvate; 2,4-Dioxo-4-(2-chlorophenyl)butanoic Acid Methyl Ester; Methyl 4-(o-Chlorophenyl)-2,4-dioxobutanoate
EINECS	Contact for details

Quality Control

Every batch of Methyl 4-(2-Chlorophenyl)-2,4-Dioxobutanoate is produced under strict quality management protocols. We employ advanced analytical techniques including HPLC, GC, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.