Description

4-({[(4-Methoxyphenyl)Sulfonyl]Amino}Methyl)Benzoic Acid is a high-purity, synthetic organic compound featuring a benzoic acid core functionalized with a sulfonamido-methyl linker and a 4-methoxyphenyl group. This specific molecular architecture makes it a valuable pharmaceutical intermediate and building block for medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly those targeting enzymes or receptors where the sulfonamide and benzoic acid moieties are critical for binding.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) and develop new chemical entities.
• Protease Inhibitor Synthesis: The sulfonamide group is a common pharmacophore in inhibitors for various proteases, making this compound a relevant precursor.
• Chemical Biology Probe Development: Can be functionalized further to create tool compounds for studying biological pathways and target validation.
• Agrochemical Intermediate: Serves as a precursor in the development of new herbicides or fungicides with novel modes of action.
• Material Science Research: Potential use as a monomer or cross-linker in the synthesis of specialized polymers with specific thermal or chemical properties.

Basic Information

Product Name	4-({[(4-Methoxyphenyl)Sulfonyl]Amino}Methyl)Benzoic Acid
CAS No.	451484-12-1
Molecular Formula	C15H15NO5S
Molecular Weight	321.35 g/mol
Synonyms	4-[[(4-Methoxyphenyl)sulfonyl]aminomethyl]benzoic acid; Benzoic acid, 4-[[(4-methoxyphenyl)sulfonyl]amino]methyl]-; 4-((4-Methoxybenzenesulfonamido)methyl)benzoic acid; 4-(N-(4-Methoxybenzenesulfonyl)aminomethyl)benzoic acid; p-((p-Methoxybenzenesulfonamido)methyl)benzoic acid; CAS 451484-12-1
EINECS	Contact for details

Quality Control

Our 4-({[(4-Methoxyphenyl)Sulfonyl]Amino}Methyl)Benzoic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.