Description

Ethyl 5-Bromo-2-Iodobenzoate is a high-purity, multi-halogenated aromatic ester building block essential for advanced organic synthesis. This compound matters because it provides a versatile and reactive scaffold for constructing complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), liquid crystal materials, and functionalized ligands for catalysis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and fungicides with enhanced efficacy.
• Material Science: Serves as a building block for organic electronic materials, including organic light-emitting diodes (OLEDs) and semiconductors.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Negishi cross-coupling reactions to form biaryl structures.
• Ligand Preparation: Utilized in the synthesis of sophisticated ligands for transition metal catalysis.
• Chemical Research: Employed in academic and industrial laboratories for method development and exploring new reaction pathways.

Basic Information

Product Name	Ethyl 5-Bromo-2-Iodobenzoate
CAS No.	450412-27-8
Molecular Formula	C9H8BrIO2
Molecular Weight	354.97 g/mol
Synonyms	Benzoic acid, 5-bromo-2-iodo-, ethyl ester; Ethyl 5-bromo-2-iodobenzoate; 5-Bromo-2-iodobenzoic acid ethyl ester; 2-Iodo-5-bromobenzoic acid ethyl ester; Ethyl 2-iodo-5-bromobenzoate; 450412-27-8; AI3-28600
EINECS	Contact for details

Quality Control

Our Ethyl 5-Bromo-2-Iodobenzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.