Description

1-Bromo-2-Iodo-3-Methoxybenzene is a high-purity, multi-halogenated aromatic building block of significant importance in advanced organic synthesis. Its unique structure, featuring both bromine and iodine substituents on a methoxybenzene scaffold, makes it a versatile and valuable precursor for constructing complex molecules. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in cross-coupling reactions, material science, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of complex drug candidates, particularly in Suzuki-Miyaura, Stille, and other palladium-catalyzed cross-coupling reactions.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the halogenated benzene core is a critical structural motif.
• Material Science & OLED Development: Serves as a building block for creating novel organic semiconductors, liquid crystals, and light-emitting materials.
• Ligand & Catalyst Synthesis: Employed in the preparation of specialized phosphine or N-heterocyclic carbene (NHC) ligands for catalysis.
• Chemical Biology & Probe Development: Useful for synthesizing molecular probes and tags due to the reactivity of the halogen atoms for further functionalization.
• Academic & Contract Research: Essential for methodological studies in organic chemistry and for custom synthesis projects in CROs (Contract Research Organizations).

Basic Information

Product Name	1-Bromo-2-Iodo-3-Methoxybenzene
CAS No.	450412-22-3
Molecular Formula	C7H6BrIO
Molecular Weight	312.93 g/mol
Synonyms	2-Bromo-1-Iodo-3-Methoxybenzene; 3-Methoxy-1-bromo-2-iodobenzene; 1-Bromo-2-iodo-3-methoxy-benzene; 2-Iodo-3-methoxybromobenzene; (2-Bromo-6-iodophenyl) methyl ether; Benzene, 1-bromo-2-iodo-3-methoxy-; 3-Methoxy-2-iodobromobenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-2-Iodo-3-Methoxybenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, assay, and impurity profiles. Our quality commitment ensures material consistency and reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.