Description

1,3,2-Dioxaborolane, 2-(1-Cycloocten-1-Yl)-4,4,5,5-Tetramethyl- is a specialized organoboron reagent featuring a cyclic dioxaborolane (pinacol boronate ester) moiety tethered to a cyclooctene ring. This compound matters as a versatile and stable synthetic intermediate, enabling critical carbon-carbon and carbon-heteroatom bond-forming reactions in advanced organic synthesis. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for constructing complex molecular architectures.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: Acts as a key boron-containing coupling partner for the palladium-catalyzed synthesis of biaryl and vinyl-aryl compounds, a cornerstone of modern medicinal chemistry.
• Synthesis of Complex Natural Products & APIs: Used in the strategic introduction of the cyclooctenyl fragment into target molecules for drug discovery and development of Active Pharmaceutical Ingredients (APIs).
• Polymer & Advanced Materials Chemistry: Serves as a functional monomer or cross-linking agent in the development of novel polymers with tailored properties, including stimuli-responsive materials.
• Ligand & Catalyst Development: Employed in the preparation of novel chelating ligands or organometallic catalysts where the cyclooctene backbone provides unique steric and electronic properties.
• Chemical Biology & Probe Synthesis: Utilized for the site-specific labeling or functionalization of biomolecules and the creation of chemical probes for biological target identification.
• Agrochemical Intermediate: Functions as a building block in the synthesis of novel crop protection agents and herbicides.

Basic Information

Product Name	1,3,2-Dioxaborolane, 2-(1-Cycloocten-1-Yl)-4,4,5,5-Tetramethyl-
CAS No.	448211-45-8
Molecular Formula	C₁₆H₂₇BO₂
Molecular Weight	262.20 g/mol
Synonyms	2-(Cyclooct-1-en-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 1-Cyclooctene-1-boronic acid pinacol ester; Cyclooct-1-en-1-ylboronic acid pinacol ester; (Cyclooct-1-en-1-yl)pinacolborane; (Cyclooct-1-en-1-yl)BPin; Cyclooctenyl pinacol boronate; Cyclooctenyl-BPin; B-(1-Cycloocten-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our high-purity organoboron reagents are manufactured under strict quality management protocols. Each batch of 1,3,2-Dioxaborolane, 2-(1-Cycloocten-1-Yl)-4,4,5,5-Tetramethyl- undergoes rigorous analytical testing, including NMR (¹H, ¹³C, ¹¹B) and HPLC analysis, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full specification data are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C to maximize shelf life and prevent oxidation and hydrolysis. Allow the sealed container to reach ambient temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95.0% (Typical: 97-99%)
Assay (NMR)	≥95.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.