Description

4,4,5,5-Tetramethyl-2-(2-Methyl-1-Cyclohexen-1-Yl)-1,3,2-Dioxaborolane is a high-value, cyclic boronic ester derivative, a key intermediate in modern synthetic organic chemistry. Its primary value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex carbon-carbon bonds. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity building blocks for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require specific, complex molecular architectures.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as polymers and small molecules for OLEDs and organic photovoltaics.
• Chemical Biology & Medicinal Chemistry: Employed in the synthesis of molecular probes, bio-conjugates, and tool compounds for target identification and validation.
• Academic & Industrial R&D: A staple reagent in laboratory-scale organic synthesis for method development and the exploration of new chemical spaces.
• Fine Chemical Production: Facilitates the scalable synthesis of complex, high-value specialty chemicals used in flavors, fragrances, and performance additives.

Basic Information

Product Name	4,4,5,5-Tetramethyl-2-(2-Methyl-1-Cyclohexen-1-Yl)-1,3,2-Dioxaborolane
CAS No.	448211-43-6
Molecular Formula	C13H23BO2
Molecular Weight	222.13 g/mol
Synonyms	2-(2-Methyl-1-cyclohexen-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2-Methyl-1-cyclohexen-1-ylboronic acid pinacol ester; (2-Methylcyclohex-1-en-1-yl)boronic acid pinacol ester; 2-Methyl-1-cyclohexenylboronic acid pinacol ester; Pinacol (2-methyl-1-cyclohexen-1-yl)boronate; 448211-43-6; B-(2-Methyl-1-cyclohexenyl)pinacolborane
EINECS	Contact for details

Quality Control

Our 4,4,5,5-Tetramethyl-2-(2-Methyl-1-Cyclohexen-1-Yl)-1,3,2-Dioxaborolane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot undergoes comprehensive analytical testing, including NMR (¹H, ¹³C, ¹¹B), HPLC, and GC analysis, to confirm identity, purity, and the absence of critical impurities. A detailed Certificate of Analysis (COA) is provided with every shipment, and we support compliance with relevant regulatory frameworks for our customers' target markets.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, this material should be handled and stored under an inert atmosphere (argon or nitrogen) to maintain stability and purity. Recommended long-term storage temperature is 2-8°C. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.