Description

[6-[Benzoyl(Methyl)Amino]-5-Methyl-3-Pyridyl]Boronic Acid is a specialized boronic acid derivative featuring a benzoylated amino-pyridine scaffold, making it a valuable building block in modern synthetic chemistry. Its core value lies in its role as a key intermediate in cross-coupling reactions, enabling the efficient construction of complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active ingredients and advanced materials. The CAS number for this compound is 446299-81-6.

Application

This boronic acid derivative is a versatile intermediate with significant utility in several high-value chemical synthesis areas.

• Pharmaceutical Intermediate: Serves as a critical precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in kinase inhibitor and other small-molecule therapeutic research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where its structural motif can contribute to biological activity.
• Material Science Research: Acts as a building block for creating organic electronic materials, such as those used in OLEDs or organic semiconductors.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and sensors that leverage boronic acid's affinity for diols, useful in carbohydrate sensing.
• Catalyst Ligand Development: The pyridine and boronic acid functionalities make it a candidate for developing novel ligands in transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses serving the life sciences sector, enabling the production of bespoke, complex molecules.

Basic Information

Item	Detail
Product Name	[6-[Benzoyl(Methyl)Amino]-5-Methyl-3-Pyridyl]Boronic Acid
CAS No.	446299-81-6
Molecular Formula	C14H15BN2O3
Molecular Weight	270.10 g/mol
Synonyms	5-Methyl-6-(N-methylbenzamido)pyridin-3-ylboronic acid; (5-Methyl-6-((methylamino)carbonyl)phenyl-3-pyridinyl)boronic acid; 6-(Benzoyl(methyl)amino)-5-methylpyridin-3-ylboronic acid; 3-Pyridineboronic acid, 6-[benzoyl(methyl)amino]-5-methyl-; B-[6-[Benzoyl(methyl)amino]-5-methyl-3-pyridyl]boronic acid
EINECS	Contact for details

Quality Control

Our [6-[Benzoyl(Methyl)Amino]-5-Methyl-3-Pyridyl]Boronic Acid is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when prolonged exposure is anticipated to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.