Description

4-(2-Fluorobenzoyl)-1-Methyl-1H-Pyrrole-2-Carbaldehyde is a high-purity fluorinated pyrrole derivative, serving as a critical advanced intermediate in modern organic synthesis. Its unique molecular structure, featuring both a fluorobenzoyl and a formyl group on the pyrrole ring, makes it an essential building block for constructing complex pharmacophores. This compound is primarily required by research institutions and pharmaceutical development companies engaged in the discovery and synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring fluorinated heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory applications.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, where the fluorinated pyrrole structure can contribute to enhanced biological activity and environmental stability.
• Material Science: Serves as a monomer or functionalizing agent in the synthesis of specialized polymers and organic electronic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and protein-ligand interactions due to its reactive aldehyde group.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and exploring new chemical spaces in heterocyclic chemistry.

Basic Information

Product Name	4-(2-Fluorobenzoyl)-1-Methyl-1H-Pyrrole-2-Carbaldehyde
CAS No.	446275-97-4
Molecular Formula	C13H10FNO2
Molecular Weight	231.22 g/mol
Synonyms	1-Methyl-4-(2-fluorobenzoyl)-1H-pyrrole-2-carboxaldehyde; 2-Fluoro-1-[4-formyl-1-methyl-1H-pyrrol-2-yl]phenylmethanone; 4-(2-Fluorobenzoyl)-1-methyl-1H-pyrrole-2-carboxaldehyde; 1-Methyl-4-(2-fluorobenzoyl)pyrrole-2-carbaldehyde; 4-(2-Fluorobenzoyl)-1-methylpyrrole-2-carbaldehyde; 2-Formyl-1-methyl-4-(2-fluorobenzoyl)pyrrole
EINECS	Contact for details

Quality Control

Our 4-(2-Fluorobenzoyl)-1-Methyl-1H-Pyrrole-2-Carbaldehyde is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can support development projects requiring material manufactured under GMP guidelines for non-clinical studies.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. Handle and store in accordance with all applicable regulations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.