Description

2-(2,3-Dihydro-1H-Inden-5-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity organoboron reagent, specifically a pinacol boronic ester, essential for modern synthetic chemistry. Its primary value lies in enabling efficient and selective carbon-carbon bond formation, a cornerstone reaction in constructing complex molecular architectures. This compound is critically needed by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for applications such as Suzuki-Miyaura cross-coupling reactions.

Application

• Pharmaceutical Intermediate Synthesis: A key building block for constructing novel drug candidates, particularly in creating biaryl and heterobiaryl structures common in active pharmaceutical ingredients (APIs).
• Agrochemical Development: Used in the research and production of advanced pesticides and herbicides, where its boronic ester functionality allows for the introduction of specific aromatic motifs.
• Material Science Research: Serves as a precursor for organic electronic materials, including polymers and small molecules for OLEDs and organic photovoltaics.
• Suzuki-Miyaura Cross-Coupling Reactions: Functions as a stable and reactive partner with aryl halides or triflates to form new carbon-carbon bonds with high efficiency and functional group tolerance.
• Chemical Biology & Probe Development: Utilized in the synthesis of molecular probes and labeled compounds for biological target identification and mechanism-of-action studies.
• Catalyst Ligand Synthesis: Acts as a starting material for the preparation of sophisticated ligand systems used in homogeneous catalysis.

Basic Information

Product Name	2-(2,3-Dihydro-1H-Inden-5-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	445303-13-9
Molecular Formula	C15H21BO2
Molecular Weight	244.14 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-indene; 2,3-Dihydro-1H-inden-5-ylboronic acid pinacol ester; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)indane; Indan-5-ylboronic acid pinacol ester; 2-(2,3-Dihydro-1H-inden-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 445303-13-9; 5-Indanylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our production of 2-(2,3-Dihydro-1H-Inden-5-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for critical R&D and scale-up processes. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and GC to confirm identity, purity, and the absence of critical impurities. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, this material should be handled and stored under an inert atmosphere (argon or nitrogen) to prevent degradation from moisture. Recommended long-term storage temperature is 2-8°C. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.