Description

1H-Imidazole-4-Carboxylic Acid, 1-(4-Bromophenyl)- is a high-value brominated imidazole derivative, a crucial building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel molecules with targeted biological or physical properties.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in kinase inhibitor and antiviral agent discovery.
• Agrochemical Synthesis: Used in the production of advanced fungicides and herbicides, leveraging the imidazole core's bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and other functional organic materials.
• Chemical Biology Probes: Utilized to develop molecular probes for studying enzyme function and cellular processes.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring a functionalized, brominated heterocycle.

Basic Information

Product Name	1H-Imidazole-4-Carboxylic Acid, 1-(4-Bromophenyl)-
CAS No.	445302-27-2
Molecular Formula	C10H7BrN2O2
Molecular Weight	267.08 g/mol
Synonyms	1-(4-Bromophenyl)-1H-imidazole-4-carboxylic acid; 4-Bromo-N-(1H-imidazol-4-yl)benzamide precursor; 1-(p-Bromophenyl)imidazole-4-carboxylic acid; 4-Carboxy-1-(4-bromophenyl)imidazole; 1-(4-Bromophenyl)-4-imidazolecarboxylic Acid; 1H-Imidazole-4-carboxylic acid, 1-(4-bromophenyl)-; 445302-27-2 (CAS)
EINECS	Contact for details

Quality Control

Our production of 1H-Imidazole-4-Carboxylic Acid, 1-(4-Bromophenyl)- adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality system is designed to support cGMP and ISO standards for pharmaceutical and fine chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.