Description

1,3-Dioxolane-4-Methanol,2,2-Diethyl-α-Propyl-,(Alphar,4S)-(9Ci) is a high-purity, stereochemically defined chiral building block of significant value in advanced organic synthesis. Its unique dioxolane-protected diol structure makes it a critical intermediate for constructing complex molecules with precise stereochemistry. This compound is essential for researchers and process chemists in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs), chiral ligands, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, especially in antiviral, anticancer, and central nervous system (CNS) therapeutic areas.
• Asymmetric Catalysis: Used in the preparation of chiral ligands and catalysts for enantioselective synthesis.
• Fine Chemical Synthesis: Serves as a versatile building block for creating complex natural products, flavors, and fragrances.
• Polymer Science: Potential monomer or cross-linking agent for developing specialty polymers with tailored properties.
• Agrochemical Research: Intermediate in the development of new, more effective chiral pesticides and herbicides.
• Academic & R&D: A valuable tool for methodological development in organic chemistry and stereochemistry studies.

Basic Information

Product Name	1,3-Dioxolane-4-Methanol,2,2-Diethyl-α-Propyl-,(Alphar,4S)-(9Ci)
CAS No.	444987-65-9
Molecular Formula	C11H22O3
Molecular Weight	202.29 g/mol
Synonyms	(4S)-2,2-Diethyl-α-propyl-1,3-dioxolane-4-methanol; (4S)-2,2-Diethyl-α-propyl-1,3-dioxolane-4-methanol (9CI); 1,3-Dioxolane-4-methanol, 2,2-diethyl-α-propyl-, (αR,4S)- (9CI); (αR,4S)-2,2-Diethyl-α-propyl-1,3-dioxolane-4-methanol; Chiral Dioxolane Methanol Derivative; (4S)-Configured Dioxolane Building Block
EINECS	Contact for details

Quality Control

Our 1,3-Dioxolane-4-Methanol,2,2-Diethyl-α-Propyl-,(Alphar,4S)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure high enantiomeric excess (ee) and chemical purity. Certificates of Analysis (COA) detailing identity, assay, impurity profile, and specific rotation are provided with every shipment to guarantee consistency and traceability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.