Description

Dichloro(Di-μ-Chloro)Bis[1,3-Bis(2,6-Di-I-Propylphenyl)Imidazol-2-Ylidene]Dipalladium (Ii) is a highly active and versatile N-heterocyclic carbene (NHC) palladium(II) dimer complex, serving as a premier pre-catalyst for demanding cross-coupling reactions. Its value lies in providing exceptional thermal stability and high catalytic turnover, enabling efficient synthesis under challenging conditions. This advanced catalyst is essential for researchers and process chemists in pharmaceutical development, agrochemical research, and advanced materials science, where robust and selective C-C and C-N bond formation is critical.

Application

This sophisticated palladium catalyst is engineered for high-performance applications in synthetic chemistry:

• Pharmaceutical Intermediate Synthesis: Enabling key Buchwald-Hartwig amination and Suzuki-Miyaura cross-coupling steps in API development.
• Agrochemical Research: Facilitating the construction of complex heterocyclic frameworks for novel active ingredients.
• Advanced Material Development: Catalyzing polymerizations and the synthesis of conjugated organic molecules for electronic applications.
• Methodology & Scale-Up Studies: Ideal for developing new catalytic protocols and transitioning from lab-scale to pilot plant production.
• Asymmetric Synthesis: Serving as a precursor for chiral catalysts in the synthesis of enantiomerically pure compounds.

Basic Information

Product Name	Dichloro(Di-μ-Chloro)Bis[1,3-Bis(2,6-Di-I-Propylphenyl)Imidazol-2-Ylidene]Dipalladium (Ii)
CAS No.	444910-17-2
Molecular Formula	C54H72Cl4N4Pd2
Molecular Weight	1126.28 g/mol
Synonyms	Palladium(II) IPr Dimer; [Pd(IPr)(μ-Cl)Cl]2; Dichloro(μ-chloro)bis[1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene]dipalladium; Pd-IPr Dimer; PEPPSI™-type Precursor; NHC-Pd(II) Dimer Complex; Bis(N,N'-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)dichlorodi-μ-chlorodipalladium
EINECS	Contact for details

Quality Control

Our production of this high-value catalyst adheres to stringent quality protocols to ensure batch-to-batch consistency and optimal catalytic performance. Each lot is characterized by NMR (1H, 13C), Elemental Analysis (EA), and HPLC to verify identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We operate under a cGMP-compliant quality management system suitable for supporting pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C to prevent oxidation and decomposition. The container should be kept in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Palladium (Pd) Content	18.5 - 19.5%
Solubility	Soluble in dichloromethane, toluene; slightly soluble in THF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.