Description

Ethyl 2-Bromo-5-(Trifluoromethyl)-1H-Imidazole-4-Carboxylate is a high-value, multi-functional heterocyclic building block designed for advanced synthetic chemistry. Its core value lies in the strategic combination of a reactive bromo substituent and a stable trifluoromethyl group on the imidazole core, enabling precise molecular modifications. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries who require reliable, high-purity intermediates for developing novel active ingredients.

Application

This specialized imidazole derivative serves as a versatile intermediate in the synthesis of complex molecules. Its primary applications include:

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors, antiviral agents, and anti-inflammatory compounds.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the trifluoromethyl group.
• Material Science Research: Serves as a precursor for functionalized ligands or monomers in the development of advanced polymers and specialty materials.
• Chemical Biology Probes: Utilized in the creation of tagged molecules or probes for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	Ethyl 2-Bromo-5-(Trifluoromethyl)-1H-Imidazole-4-Carboxylate
CAS No.	444326-49-2
Molecular Formula	C7H6BrF3N2O2
Molecular Weight	287.04 g/mol
Synonyms	Ethyl 2-bromo-5-(trifluoromethyl)-1H-imidazole-4-carboxylate; 1H-Imidazole-4-carboxylic acid, 2-bromo-5-(trifluoromethyl)-, ethyl ester; 2-Bromo-5-(trifluoromethyl)-1H-imidazole-4-carboxylic acid ethyl ester; 4-Carbethoxy-2-bromo-5-trifluoromethylimidazole; Ethyl 2-bromo-5-trifluoromethylimidazole-4-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 2-Bromo-5-(Trifluoromethyl)-1H-Imidazole-4-Carboxylate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality systems support development from research quantities to commercial scale, ensuring reliable supply for GMP and non-GMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Standard Grade)
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤1.0%
Total Impurities (HPLC)	≤3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.