Description

3-((4-((4-Butylphenyl)(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Amino)Phenyl)(Methyl)Bo is a high-purity, functionalized aryl boronic ester pinacol derivative, a critical intermediate in modern synthetic organic chemistry. Its value lies in its role as a versatile building block for Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly in the development of active pharmaceutical ingredients (APIs), liquid crystal materials, and organic light-emitting diodes (OLEDs).

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, especially those containing complex biaryl motifs common in kinase inhibitors and other targeted therapies.
• OLED Material Synthesis: Used in the production of hole-transporting materials (HTMs), host materials, and emitters for high-performance display and lighting technologies.
• Liquid Crystal Manufacturing: Serves as a precursor for creating advanced liquid crystal molecules used in displays (LCDs) with specific electro-optical properties.
• Agrochemical Development: Intermediate in the synthesis of new-generation herbicides, fungicides, and insecticides that require specific aromatic architectures.
• Polymer & Material Science: Enables the incorporation of functional aromatic units into polymers, dendrimers, and other advanced materials for tailored properties.
• Academic & Industrial R&D: A valuable reagent for method development and exploring new synthetic pathways in cross-coupling chemistry.

Basic Information

Item	Details
Product Name	3-((4-((4-Butylphenyl)(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Amino)Phenyl)(Methyl)Bo
CAS No.	444289-55-8
Molecular Formula	C33H43BN2O2
Molecular Weight	510.52 g/mol
Synonyms	N-(4-Butylphenyl)-N-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-3-(methylamino)benzeneboronic acid pinacol ester; 3-[(4-{[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl](4-butylphenyl)amino}phenyl)(methyl)amino]benzeneboronic acid pinacol ester; Boronic acid, B-[3-[[4-[[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl](4-butylphenyl)amino]phenyl]methylamino]phenyl]-, pinacol ester; Aryl boronic ester pinacol derivative; Triarylamine-based boronate; Suzuki coupling reagent.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analysis using techniques including HPLC, NMR (1H, 13C, 11B), and mass spectrometry to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key specifications. We support development under cGMP guidelines where required for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and during weighing to prevent hydrolysis of the boronic ester group. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.