Description

1-[(3-Chloro-6-Methoxy-1-Benzothien-2-Yl)Carbonyl]-1,2,3,4-Tetrahydroquinoline is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel, biologically active molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders or other specialized therapeutic areas.
• Medicinal Chemistry Research: Used as a scaffold or core structure for constructing compound libraries in high-throughput screening (HTS) campaigns to identify new lead molecules.
• Process Chemistry Development: Serves as a key material for optimizing and scaling up synthetic routes during the drug development lifecycle from discovery to clinical trials.
• Academic Research: Employed in university and institutional labs for studying structure-activity relationships (SAR) and novel organic reaction methodologies involving fused heterocyclic systems.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations that support pharmaceutical companies with custom synthesis and development services.

Basic Information

Product Name	1-[(3-Chloro-6-Methoxy-1-Benzothien-2-Yl)Carbonyl]-1,2,3,4-Tetrahydroquinoline
CAS No.	444059-85-2
Molecular Formula	C19H16ClNO2S
Molecular Weight	357.85 g/mol
Synonyms	1-[(3-Chloro-6-methoxy-1-benzothiophen-2-yl)carbonyl]-1,2,3,4-tetrahydroquinoline; 1-(3-Chloro-6-methoxybenzo[b]thiophene-2-carbonyl)-1,2,3,4-tetrahydroquinoline; 444059-85-2; Tetrahydroquinoline derivative, benzothiophene-substituted; 3-Chloro-6-methoxy-N-(1,2,3,4-tetrahydroquinolin-1-yl)benzo[b]thiophene-2-carboxamide
EINECS	Contact for details

Quality Control

Our production of 1-[(3-Chloro-6-Methoxy-1-Benzothien-2-Yl)Carbonyl]-1,2,3,4-Tetrahydroquinoline adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere when appropriate to ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.