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(11Ar)-(+)-10,11,12,13-Tetrahydrodiindeno[7,1-De:1',7'-Fg][1,3,2]Dioxaphosphocin-5-Dimethylamine CAS NO 443965-14-8


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CAS No.:443965-14-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(11Ar)-(+)-10,11,12,13-Tetrahydrodiindeno[7,1-De:1',7'-Fg][1,3,2]Dioxaphosphocin-5-Dimethylamine is a sophisticated chiral organophosphorus compound, valued for its unique structural framework and potential as a key intermediate or ligand in advanced chemical synthesis. Its significance lies in enabling precise stereochemical control and facilitating novel reaction pathways in research and development. This high-purity specialty chemical is primarily needed by the pharmaceutical, agrochemical, and advanced materials sectors for applications in catalysis, asymmetric synthesis, and the development of new active ingredients.

Application

  • Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly those requiring chiral phosphine or phosphonite ligands.
  • Asymmetric Catalysis: Acts as a precursor or ligand for transition metal catalysts used in enantioselective hydrogenation, cross-coupling, and other stereospecific transformations.
  • Agrochemical Research: Employed in the development of new pesticides and herbicides where its unique phosphorus-containing structure can impart specific biological activity.
  • Material Science: Used in the research of advanced polymers, ligands for metal-organic frameworks (MOFs), or other functional materials.
  • Academic & Industrial R&D: A valuable tool for chemists exploring new methodologies in organometallic chemistry and synthetic organic chemistry.
  • Ligand Synthesis: Directly utilized as a chiral ligand or modified to create a library of related phosphine/phosphite ligands for catalytic systems.

Basic Information

Product Name (11Ar)-(+)-10,11,12,13-Tetrahydrodiindeno[7,1-De:1',7'-Fg][1,3,2]Dioxaphosphocin-5-Dimethylamine
CAS No. 443965-14-8
Molecular Formula C23H22NOP
Molecular Weight 359.40 g/mol
Synonyms (+)-DTDP-Dimethylamine; (11Ar)-(+)-DTDP-NMe2; (11Ar)-(+)-10,11,12,13-Tetrahydrodiindeno[7,1-de:1',7'-fg][1,3,2]dioxaphosphocine-5-dimethylamine; 5-(Dimethylamino)-10,11,12,13-tetrahydrodiindeno[7,1-de:1',7'-fg][1,3,2]dioxaphosphocine; Chiral DTDP amine derivative; (11aR)-(+)-5-(Dimethylamino)-10,11,12,13-tetrahydrodiindeno[7,1-de:1',7'-fg][1,3,2]dioxaphosphocine
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Quality Control

Our production of (11Ar)-(+)-10,11,12,13-Tetrahydrodiindeno[7,1-De:1',7'-Fg][1,3,2]Dioxaphosphocin-5-Dimethylamine adheres to stringent quality protocols to ensure batch-to-batch consistency and high chiral purity. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and chiral analysis. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be sensitive to moisture and oxygen; for long-term storage, consider under an inert atmosphere.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Enantiomeric Excess (Chiral HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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