Description

2-Bromo-1-(5-Fluoro-2-Methoxy-Phenyl)-Ethanone is a high-purity, specialized brominated aromatic ketone building block of significant interest in advanced organic synthesis. Its core value lies in its precise molecular architecture, featuring both bromo and fluoro substituents, which enables selective functionalization and the construction of complex heterocyclic scaffolds. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, serving as a critical intermediate for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders, due to its fluorinated aromatic structure.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and insecticides, where the bromo and fluoro groups contribute to biological activity and metabolic stability.
• Material Science Research: Serves as a building block for creating advanced organic materials, such as liquid crystals or organic semiconductors, where specific halogen substitution patterns are required.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for studying biological processes and protein interactions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	2-Bromo-1-(5-Fluoro-2-Methoxy-Phenyl)-Ethanone
CAS No.	443914-95-2
Molecular Formula	C9H8BrFO2
Molecular Weight	247.06 g/mol
Synonyms	2-Bromo-1-(5-fluoro-2-methoxyphenyl)ethanone; 5'-Fluoro-2'-methoxy-2-bromoacetophenone; 2-Bromo-5'-fluoro-2'-methoxyacetophenone; 1-(5-Fluoro-2-methoxyphenyl)-2-bromoethanone; α-Bromo-5-fluoro-2-methoxyacetophenone; 2-Bromo-1-(5-fluoro-2-methoxyphenyl)ethan-1-one; 443914-95-2
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-1-(5-Fluoro-2-Methoxy-Phenyl)-Ethanone is manufactured and tested under strict quality management systems to ensure consistent purity and performance. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards and customer-specific requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.