Description

3-Bromo-4-(4-Methyl-Piperazin-1-Yl)-Benzaldehyde is a high-value, multi-functional aromatic aldehyde building block featuring a bromine substituent and a methylpiperazine moiety. This compound is essential for its role as a key synthetic intermediate in the development of advanced pharmaceutical compounds and specialty organic materials. It is primarily sought after by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Serves as a building block for developing novel crop protection agents and herbicides.
• Material Science: Used in the research and synthesis of advanced organic materials, including ligands for catalysis and functional polymers.
• Chemical Biology: Employed as a probe or linker in the development of biochemical tools and diagnostic agents.
• Academic & Contract Research: A valuable reagent for methodological development and exploratory organic synthesis in academic and CRO laboratories.

Basic Information

Product Name	3-Bromo-4-(4-Methyl-Piperazin-1-Yl)-Benzaldehyde
CAS No.	443777-03-5
Molecular Formula	C13H17BrN2O
Molecular Weight	297.19 g/mol
Synonyms	4-(3-Bromo-4-formylphenyl)-1-methylpiperazine; 1-Methyl-4-(3-bromo-4-formylphenyl)piperazine; 3-Bromo-4-(1-methyl-4-piperazinyl)benzaldehyde; 3-Bromo-4-(N-methylpiperazinyl)benzaldehyde; Benzaldehyde, 3-bromo-4-(4-methyl-1-piperazinyl)-; 443777-03-5; 3-Bromo-4-(4-methylpiperazin-1-yl)benzaldehyde
EINECS	Contact for details

Quality Control

We maintain a strict quality management system to ensure batch-to-batch consistency and high purity. Our standard grade for this intermediate typically meets a purity specification of ≥95% (by HPLC), with options for higher grades (≥98%, ≥99%) available. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. Our manufacturing and quality processes are designed to support development under cGMP guidelines as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage or after opening. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.