Description

4-Methoxy-3-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzaldehyde is a versatile and high-value boronic ester derivative, serving as a critical synthetic intermediate in modern organic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone of pharmaceutical and advanced materials research. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and organic electronics industries who require reliable, high-purity building blocks for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and plant growth regulators that require specific aryl-aldehyde functionalities.
• Material Science & OLED Development: Employed in the synthesis of organic semiconductors, charge-transport materials, and light-emitting molecules for electronic displays and devices.
• Ligand & Catalyst Preparation: Serves as a precursor for creating sophisticated ligands used in asymmetric catalysis and transition metal complexes.
• Chemical Biology & Probe Synthesis: Utilized to create molecular probes and labeled compounds for biochemical assays and diagnostic research.
• Polymer & Resin Modification: Acts as a functional monomer or cross-linking agent for introducing aldehyde and boronate ester groups into polymer chains.

Basic Information

Product Name	4-Methoxy-3-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzaldehyde
CAS No.	443776-90-7
Molecular Formula	C14H19BO4
Molecular Weight	262.11 g/mol
Synonyms	3-Formyl-4-methoxyphenylboronic acid pinacol ester; 4-Methoxy-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-methoxybenzaldehyde; 4-Methoxy-3-(pinacolatoboryl)benzaldehyde; 3-Aldehyde-4-methoxyphenylboronic acid pinacol ester; Pinacol [3-formyl-4-methoxyphenyl]boronate; 3-(Pinacolatoboryl)-4-methoxybenzaldehyde
EINECS	Contact for details

Quality Control

Our 4-Methoxy-3-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.