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(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Methanol CAS NO 443776-76-9


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CAS No.:443776-76-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Methanol is a high-value boronic ester derivative, serving as a versatile synthetic intermediate in modern organic chemistry. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and conjugated systems. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where precise carbon-carbon bond formation is critical for developing active ingredients and functional molecules.

Application

  • Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those containing biphenyl or substituted phenyl motifs.
  • Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides that require specific aromatic architectures.
  • Material Science: Serves as a monomer or precursor in the development of organic electronic materials, such as OLEDs and conductive polymers.
  • Ligand & Catalyst Development: Employed in the preparation of sophisticated ligands for transition metal catalysis and organoboron reagents.
  • Chemical Research: A valuable tool in academic and industrial R&D for exploring new synthetic pathways and creating compound libraries.
  • Fine Chemical Production: Integral to the multi-step synthesis of complex, high-value specialty chemicals and flavors/fragrances.

Basic Information

Product Name (3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Methanol
CAS No. 443776-76-9
Molecular Formula C13H19BO3
Molecular Weight 234.10 g/mol
Synonyms 3-(Hydroxymethyl)phenylboronic acid pinacol ester; (3-(Hydroxymethyl)phenyl)boronic acid pinacol ester; [3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methanol; 3-(Pinacolatoboryl)benzyl alcohol; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzenemethanol; Pinacol (3-(hydroxymethyl)phenyl)boronate
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Quality Control

Our (3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Methanol is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to prevent degradation.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Assay (HPLC) ≥97.0%
Water Content (KF) ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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