Description

2-Methyl-10,11-Dihydro-Dibenzo[B,F][1,4]Oxazepine CAS NO 443749-33-5 is a high-purity, heterocyclic organic compound belonging to the dibenzoxazepine class, serving as a crucial advanced pharmaceutical intermediate and a versatile building block in synthetic organic chemistry. Its unique tricyclic structure makes it invaluable for the research and development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and other therapeutic areas. This compound is essential for pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in innovative drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel psychotropic and neuroactive drug candidates.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Organic Synthesis Building Block: Employed in the construction of complex polycyclic molecules for material science and chemical biology applications.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Research: Investigated for its potential interactions with various biological receptors and enzymes.
• Process Chemistry Development: Utilized in route scouting and optimization for the scalable synthesis of target molecules.

Basic Information

Product Name	2-Methyl-10,11-Dihydro-Dibenzo[B,F][1,4]Oxazepine
CAS No.	443749-33-5
Molecular Formula	C₁₅H₁₃NO
Molecular Weight	223.27 g/mol
Synonyms	2-Methyl-10,11-dihydrodibenzo[b,f][1,4]oxazepine; 10,11-Dihydro-2-methyl-dibenzo[b,f][1,4]oxazepine; Dibenzo[b,f][1,4]oxazepine, 10,11-dihydro-2-methyl-; 2-Methyldibenz[b,f][1,4]oxazepine; Loxapine Impurity; Loxapine Related Compound; 2-Methyl-10,11-dihydrodibenz[b,f][1,4]oxazepine
EINECS	Contact for details

Quality Control

Our 2-Methyl-10,11-Dihydro-Dibenzo[B,F][1,4]Oxazepine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters to support your quality assurance and regulatory needs. Our production adheres to cGMP principles suitable for pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.