Description

1-(3-Bromo-4-Methylbenzoyl)Pyrrolidine is a high-purity, advanced pharmaceutical intermediate characterized by its specific brominated aromatic structure. This compound is critical for synthetic chemists in the research and development of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers requiring a reliable, high-quality building block for complex organic synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially in medicinal chemistry programs.
• Organic Synthesis Reagent: Used in cross-coupling reactions, amide bond formations, and as a precursor for more complex heterocyclic systems.
• Research & Development: Serves as a crucial material in academic and industrial R&D for exploring new chemical entities and pharmacological pathways.
• Agrochemical Synthesis: Potential intermediate in the development of new crop protection agents and herbicides.
• Material Science: Can be investigated as a monomer or precursor for specialty polymers and advanced organic materials.

Basic Information

Product Name	1-(3-Bromo-4-Methylbenzoyl)Pyrrolidine
CAS No.	443638-10-6
Molecular Formula	C12H14BrNO
Molecular Weight	268.15 g/mol
Synonyms	1-[(3-Bromo-4-methylphenyl)carbonyl]pyrrolidine; 3-Bromo-4-methyl-N-pyrrolidin-1-ylbenzamide; 1-(3-Bromo-p-toluoyl)pyrrolidine; N-(3-Bromo-4-methylbenzoyl)pyrrolidine; Pyrrolidine, 1-[(3-bromo-4-methylphenyl)carbonyl]-; 443638-10-6; (3-Bromo-4-methylbenzoyl)pyrrolidine
EINECS	Contact for details

Quality Control

Our 1-(3-Bromo-4-Methylbenzoyl)Pyrrolidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) for every shipment, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.