Description

11-(4-(2-(p-Tolyloxy)Ethyl)Piperazin-1-Yl)-2,3-Dihydro-1H-Benzo[4,5]Imidazo[1,2-A]Cyclopenta[D]Pyridine-4-Carbonitrile CAS NO 443332-24-9 is a high-purity, complex heterocyclic organic compound featuring a fused benzimidazocyclopentapyridine core linked to a piperazine-tolyloxy pharmacophore. This molecular architecture makes it a critical advanced intermediate for pharmaceutical research and development, particularly in the synthesis of novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery programs targeting central nervous system (CNS) disorders, oncology, and other specialized therapeutic areas.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, especially those targeting neurological receptors.
• Research Chemical: Used in academic and industrial R&D for structure-activity relationship (SAR) studies and biological screening.
• Preclinical Development: Employed in the preparation of compounds for pharmacological evaluation, toxicology studies, and metabolic profiling.
• Chemical Biology Probe: Utilized to study specific biological pathways and protein interactions due to its complex, drug-like structure.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Custom Synthesis: A starting material for the contract manufacturing of specialized, non-commercial compounds for client-specific research projects.

Basic Information

Item	Detail
Product Name	11-(4-(2-(p-Tolyloxy)Ethyl)Piperazin-1-Yl)-2,3-Dihydro-1H-Benzo[4,5]Imidazo[1,2-A]Cyclopenta[D]Pyridine-4-Carbonitrile
CAS No.	443332-24-9
Molecular Formula	C30H29N5O
Molecular Weight	475.59 g/mol
Synonyms	11-[4-[2-(4-Methylphenoxy)ethyl]piperazin-1-yl]-2,3-dihydro-1H-benzo[4,5]imidazo[1,2-a]cyclopenta[d]pyridine-4-carbonitrile; BICP Nitrile Derivative; 443332-24-9; 11-(4-(2-(p-Tolyloxy)ethyl)piperazin-1-yl)-2,3-dihydro-1H-benzo[4,5]imidazo[1,2-a]cyclopenta[d]pyridine-4-carbonitrile; Benzimidazocyclopentapyridine-carbonitrile piperazine derivative; 4-Cyano-11-(4-(2-(p-tolyloxy)ethyl)piperazin-1-yl)-2,3-dihydro-1H-benzo[4,5]imidazo[1,2-a]cyclopenta[d]pyridine
EINECS	Contact for details

Quality Control

Our 11-(4-(2-(p-Tolyloxy)Ethyl)Piperazin-1-Yl)-2,3-Dihydro-1H-Benzo[4,5]Imidazo[1,2-A]Cyclopenta[D]Pyridine-4-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical characterization using techniques such as HPLC, NMR, and MS to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting critical quality attributes. We support cGMP compliance for advanced intermediates intended for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed in a desiccated environment and opened under inert atmosphere when handling is required for prolonged periods.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.