Description

4'-Trifluoromethyl-4-Biphenylsulfonic Acid is a specialized biphenyl derivative functionalized with a sulfonic acid group and a trifluoromethyl substituent, making it a valuable intermediate for advanced synthesis. This compound is particularly significant for its role as a key building block in the development of pharmaceuticals, agrochemicals, and functional materials, where its unique electronic and steric properties are leveraged. It is primarily sought by research institutions and industrial manufacturers in the life sciences and specialty chemical sectors for creating novel active ingredients and high-performance polymers.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system and metabolic disorders.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for polar components in liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs) due to its biphenyl core and strong electron-withdrawing groups.
• Polymer Modification: Employed to introduce sulfonic acid functionality into polymers, creating ion-exchange resins, proton-conducting membranes for fuel cells, and specialty coatings.
• Catalyst & Ligand Preparation: Utilized in the design of organometallic catalysts and chiral ligands for asymmetric synthesis in fine chemical production.
• Dye & Pigment Manufacturing: Acts as an intermediate for synthesizing high-value, color-fast dyes and organic pigments.

Basic Information

Product Name	4'-Trifluoromethyl-4-Biphenylsulfonic Acid
CAS No.	443143-60-0
Molecular Formula	C13H9F3O3S
Molecular Weight	302.27 g/mol
Synonyms	[4-(Trifluoromethyl)[1,1'-biphenyl]-4'-yl]sulfonic Acid; 4'-(Trifluoromethyl)biphenyl-4-sulfonic Acid; 4-Biphenylsulfonic Acid, 4'-trifluoromethyl-; p-Trifluoromethylbiphenyl-4'-sulfonic Acid; 4-(4'-Trifluoromethylphenyl)benzenesulfonic Acid; 4'-Trifluoromethyl[1,1'-biphenyl]-4-sulfonic Acid
EINECS	Contact for details

Quality Control

Our 4'-Trifluoromethyl-4-Biphenylsulfonic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its strong acid nature, keep away from incompatible materials such as bases, oxidizing agents, and reactive metals. The container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.