Description

7-Fluoro-5-Methyl Isatin is a strategically fluorinated and methylated derivative of the versatile isatin scaffold, offering enhanced reactivity and specific electronic properties for advanced synthesis. This compound is a critical building block for medicinal chemistry research, enabling the development of novel pharmaceutical candidates with targeted biological activity. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new molecular entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex heterocyclic compounds and potential drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the fluorine atom can improve metabolic stability and bioactivity.
• Organic Synthesis Building Block: Serves as a versatile starting material for constructing indole, quinoline, and other fused ring systems via condensation and cyclization reactions.
• Material Science: Investigated for the preparation of functional dyes, pigments, and organic electronic materials due to its conjugated structure.
• Biochemical Probe Development: Utilized in designing enzyme inhibitors and receptor ligands for biochemical and pharmacological studies.

Basic Information

Product Name	7-Fluoro-5-Methyl Isatin
CAS No.	442910-92-1
Molecular Formula	C9H6FNO2
Molecular Weight	179.15 g/mol
Synonyms	7-Fluoro-5-methyl-1H-indole-2,3-dione; 5-Methyl-7-fluoroisatin; 1H-Indole-2,3-dione, 7-fluoro-5-methyl-; 7-Fluoro-5-methylindoline-2,3-dione
EINECS	Contact for details

Quality Control

Our 7-Fluoro-5-Methyl Isatin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are kept sealed to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.