Description

3-(2-Adamantan-1-Yl-Ethyl)-2-(4-Chloro-Phenylimino)-4-Oxo-[1,3]Thiazinane-6-Carboxylic Acid CAS NO 442665-87-4 is a high-purity, advanced pharmaceutical intermediate featuring a complex molecular architecture combining adamantane and thiazinane moieties. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated chemical scaffolds. It is primarily sought by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in developing next-generation medications.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates targeting central nervous system (CNS) disorders, viral infections, or other specialized therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its unique adamantane-based hydrophobic core and functionalized heterocycle.
• API Development: Employed in the pilot-scale and commercial-scale production routes for advanced active pharmaceutical ingredients requiring this specific molecular fragment.
• Chemical Biology Probes: Utilized in the development of specialized probes for studying biological pathways and enzyme interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, complex intermediates.

Basic Information

Product Name	3-(2-Adamantan-1-Yl-Ethyl)-2-(4-Chloro-Phenylimino)-4-Oxo-[1,3]Thiazinane-6-Carboxylic Acid
CAS No.	442665-87-4
Molecular Formula	C23H27ClN2O3S
Molecular Weight	446.99 g/mol
Synonyms	3-(2-Adamantan-1-ylethyl)-2-[(4-chlorophenyl)imino]-4-oxo-1,3-thiazinane-6-carboxylic acid; 2-((4-Chlorophenyl)imino)-3-(2-(tricyclo[3.3.1.1³,⁷]decan-1-yl)ethyl)-4-oxo-1,3-thiazinane-6-carboxylic acid; 442665-87-4; 3-(2-Adamantan-1-yl-ethyl)-2-(4-chloro-phenylimino)-4-oxo-[1,3]thiazinane-6-carboxylic acid; Adamantane-thiazinane carboxylic acid derivative
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced under strict quality management systems to ensure identity, purity, and consistency. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with client specifications and cGMP (current Good Manufacturing Practice) standards where required. Comprehensive Certificates of Analysis (COA) detailing purity, impurities, and analytical results are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere if specified. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.