Description

1-(4-(5-Fluoro-2-Methoxybenzyl)Piperazin-1-Yl)-3-Methylbenzo[4,5]Imidazo[1,2-A]Pyridine-4-Carbonitrile is a sophisticated heterocyclic organic compound featuring a fused benzoimidazopyridine core, a piperazine linker, and a fluorinated methoxybenzyl group. This complex molecular architecture makes it a critical intermediate or active pharmaceutical ingredient (API) in advanced research and development. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates targeting specific biological pathways.
• Kinase Inhibitor Research: Used in the development and screening of potential kinase inhibitors for cancer therapy.
• CNS Drug Discovery: Acts as a precursor in the research of compounds for neurological and psychiatric disorders.
• Chemical Biology Probe: Utilized as a tool compound to study enzyme function and protein-ligand interactions in academic and industrial research.
• Process Chemistry Development: Employed in scaling up synthetic routes and optimizing manufacturing processes for complex APIs.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method validation in regulatory submissions.

Basic Information

Item	Details
Product Name	1-(4-(5-Fluoro-2-Methoxybenzyl)Piperazin-1-Yl)-3-Methylbenzo[4,5]Imidazo[1,2-A]Pyridine-4-Carbonitrile
CAS No.	442572-33-0
Molecular Formula	C27H25FN6O
Molecular Weight	468.53 g/mol
Synonyms	3-Methyl-1-[4-[(5-fluoro-2-methoxyphenyl)methyl]piperazin-1-yl]benzo[4,5]imidazo[1,2-a]pyridine-4-carbonitrile; 442572-33-0; UNII-6Q4F8J9Q6V; 6Q4F8J9Q6V; Benzo[4,5]imidazo[1,2-a]pyridine-4-carbonitrile, 1-[4-[(5-fluoro-2-methoxyphenyl)methyl]-1-piperazinyl]-3-methyl-; 1-(4-((5-Fluoro-2-methoxybenzyl)piperazin-1-yl)-3-methylbenzo[4,5]imidazo[1,2-a]pyridine-4-carbonitrile
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is subjected to comprehensive analytical characterization using techniques such as HPLC, NMR, and MS to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with client specifications. We support development and commercial projects with GMP-grade material upon request, manufactured under appropriate quality controls.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.