Description

(R)-Pyrrolidine-2-Carbaldehyde is a high-value, chiral building block and intermediate in organic synthesis. This compound matters for its critical role in constructing complex molecules with defined stereochemistry, enabling the development of targeted pharmaceuticals and advanced materials. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications in asymmetric synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting neurological and metabolic disorders.
• Asymmetric Catalyst Ligand Synthesis: Used to construct sophisticated ligand frameworks for transition metal catalysts employed in enantioselective reactions.
• Agrochemical Research: Serves as a building block for developing novel, chiral pesticides and herbicides with improved efficacy and environmental profiles.
• Peptidomimetics & Bioactive Molecule Design: Incorporated into the backbone of peptidomimetic compounds and other bioactive molecules to modulate their properties and interactions.
• Academic & Process Chemistry Research: Utilized in methodological development and scale-up studies for new synthetic routes requiring chiral pyrrolidine motifs.

Basic Information

Product Name	(R)-Pyrrolidine-2-Carbaldehyde
CAS No.	440361-71-7
Molecular Formula	C5H9NO
Molecular Weight	99.13 g/mol
Synonyms	(R)-2-Formylpyrrolidine; (R)-Proline Aldehyde; D-Proline Aldehyde; (R)-Pyrrolidine-2-carboxaldehyde; (2R)-Pyrrolidine-2-carbaldehyde; (R)-2-Pyrrolidinecarboxaldehyde; (R)-1,2-Didehydropyrrolidine-2-carboxaldehyde; (R)-2-Azacyclopentanecarboxaldehyde
EINECS	Contact for details

Quality Control

Our (R)-Pyrrolidine-2-Carbaldehyde is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for research and production use. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically ≥97%), enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.