Description

1-Isopropyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrrole is a high-value, organoboron building block essential for modern synthetic chemistry. Its core value lies in enabling efficient carbon-carbon and carbon-heteroatom bond formation via Suzuki-Miyaura cross-coupling reactions. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and advanced organic materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those containing pyrrole or heterocyclic motifs.
• Agrochemical Research: Used to construct novel pesticide and herbicide molecules through palladium-catalyzed cross-coupling.
• Material Science: Serves as a monomer or functionalization agent in the development of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Synthesis: An indispensable reagent for academic and industrial R&D labs performing Suzuki-Miyaura couplings to create complex molecular architectures.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands and organometallic catalysts.
• Library Synthesis: Facilitates the rapid generation of diverse compound libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	1-Isopropyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrrole
CAS No.	439813-84-0
Molecular Formula	C13H22BNO2
Molecular Weight	235.13 g/mol
Synonyms	1-Isopropyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole; 1H-Pyrrole, 1-(1-methylethyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-isopropyl-1H-pyrrole; 1-Isopropyl-3-(pinacolatoboryl)pyrrole; 3-Pinacolatoboryl-1-isopropylpyrrole; 1-Isopropyl-3-pyrrolylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 1-Isopropyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrrole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR and HPLC, to ensure high purity and consistent performance for critical coupling reactions. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.