Description

1-Benzyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrrole is a high-value organoboron building block, specifically a pyrrole-substituted boronic ester pinacol ester. This compound matters as a critical intermediate in modern synthetic chemistry, enabling efficient cross-coupling reactions to construct complex molecular architectures. Pharmaceutical, agrochemical, and advanced materials researchers need it for the development of novel active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of complex organic molecules, particularly in medicinal chemistry.
• Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs), especially those containing pyrrole or biaryl motifs.
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, and insecticides with improved efficacy.
• Material Science Research: Employed in the synthesis of organic semiconductors, conductive polymers, and advanced organic frameworks (MOFs/COFs).
• Chemical Biology & Probe Development: Useful for creating labeled compounds and molecular probes for diagnostic and research applications.
• Scale-up Process Chemistry: Suitable for use in pilot plant and commercial-scale synthesis due to its stability and handling properties.

Basic Information

Product Name	1-Benzyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrrole
CAS No.	439813-83-9
Molecular Formula	C17H24BNO2
Molecular Weight	285.19 g/mol
Synonyms	1-Benzyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole; 1-Benzyl-3-(pinacolboryl)-1H-pyrrole; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-benzyl-1H-pyrrole; 1-Benzyl-3-pyrrolylboronic acid pinacol ester; 1H-Pyrrole, 1-benzyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 439813-83-9; BRN 9080506
EINECS	Contact for details

Quality Control

Our 1-Benzyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrrole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR and HPLC, to ensure high purity and consistency suitable for research and scale-up applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (argon or nitrogen) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.