Description

5-(Bromomethyl)-4-Methyl-2-[4-(Trifluoromethyl)Phenyl]-1,3-Thiazole is a high-value, multi-functional heterocyclic building block characterized by its reactive bromomethyl group and electron-deficient trifluoromethylphenyl moiety. This compound matters for its critical role in facilitating efficient carbon-carbon and carbon-heteroatom bond formation, enabling the synthesis of complex molecular architectures. It is primarily needed by pharmaceutical and agrochemical R&D teams for constructing novel active ingredients, as well as by advanced material scientists developing specialty polymers and organic electronic components.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used in constructing advanced active ingredients for crop protection products, leveraging the bioactivity of the thiazole core.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers and functional materials.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel ligands for catalysis and sensing applications.
• Chemical Biology Probe: Utilized in bioconjugation and probe synthesis due to the reactive bromomethyl handle for attaching fluorescent or affinity tags.
• Organic Electronic Materials: Acts as a building block for electron-transport materials in OLEDs and other optoelectronic devices.

Basic Information

Product Name	5-(Bromomethyl)-4-Methyl-2-[4-(Trifluoromethyl)Phenyl]-1,3-Thiazole
CAS No.	439134-78-8
Molecular Formula	C12H9BrF3NOS
Molecular Weight	352.17 g/mol
Synonyms	4-Methyl-5-(bromomethyl)-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole; 2-(4-Trifluoromethylphenyl)-4-methyl-5-bromomethylthiazole; 5-(Bromomethyl)-4-methyl-2-(4-trifluoromethylphenyl)thiazole; 1,3-Thiazole, 5-(bromomethyl)-4-methyl-2-[4-(trifluoromethyl)phenyl]-; 439134-78-8; 5-Bromomethyl-4-methyl-2-(4-trifluoromethylphenyl)thiazole
EINECS	Contact for details

Quality Control

Our production of 5-(Bromomethyl)-4-Methyl-2-[4-(Trifluoromethyl)Phenyl]-1,3-Thiazole adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The product undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to confirm identity and quantify impurities. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with each shipment. We support compliance with cGMP and ICH Q7 guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to the light-sensitive nature of the compound, containers should be amber glass or opaque. For long-term storage, consider storage under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.