Description

(5-Bromo-1-Benzothiophen-2-Yl)(1-Pyrrolidinyl)Methanone is a high-purity, advanced pharmaceutical intermediate characterized by its distinct benzothiophene core functionalized with bromine and a pyrrolidinyl methanone group. This compound is valued for its role as a critical building block in the synthesis of novel, biologically active molecules, particularly in medicinal chemistry research and development. It is primarily sought by R&D laboratories and pharmaceutical manufacturers engaged in developing new therapeutic agents, especially those targeting central nervous system (CNS) disorders and other specialized disease areas.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of potential drug candidates, particularly those with benzothiophene-based scaffolds.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and lead optimization processes within academic and industrial R&D settings.
• CNS Drug Development: Its structural features make it relevant for the research and synthesis of compounds targeting neurological and psychiatric conditions.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme function and biological pathways.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	(5-Bromo-1-Benzothiophen-2-Yl)(1-Pyrrolidinyl)Methanone
CAS No.	439108-00-6
Molecular Formula	C₁₃H₁₂BrNOS
Molecular Weight	310.21 g/mol
Synonyms	5-Bromo-1-benzothiophen-2-yl(pyrrolidin-1-yl)methanone; 1-(5-Bromo-1-benzothiophen-2-yl)-2-pyrrolidin-1-ylethanone; (5-Bromobenzo[b]thiophen-2-yl)(pyrrolidin-1-yl)methanone; 5-Bromo-2-(1-pyrrolidinylcarbonyl)-1-benzothiophene; 439108-00-6; Methanone, (5-bromo-1-benzothiophen-2-yl)-1-pyrrolidinyl-
EINECS	Contact for details

Quality Control

Our (5-Bromo-1-Benzothiophen-2-Yl)(1-Pyrrolidinyl)Methanone is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our commitment to quality assurance supports the stringent requirements of pharmaceutical R&D and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.