Description

Ethyl 2-(1-[3-(Trifluoromethyl)Benzoyl]-4-Piperidinylidene)Acetate is a high-purity, advanced pharmaceutical intermediate featuring a piperidinylidene-acetate core functionalized with a trifluoromethylbenzoyl group. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel bioactive molecules targeting the central nervous system and other therapeutic areas. It is primarily sought by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those with potential neurological activity.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop new therapeutic agents.
• Active Pharmaceutical Ingredient (API) Development: Serves as a precursor in the multi-step synthesis of complex, high-value target molecules.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Biochemical Tool Compound: May be utilized in biochemical assays and as a probe to study specific biological pathways or receptor interactions.

Basic Information

Product Name	Ethyl 2-(1-[3-(Trifluoromethyl)Benzoyl]-4-Piperidinylidene)Acetate
CAS No.	439095-20-2
Molecular Formula	C17H18F3NO3
Molecular Weight	341.33 g/mol
Synonyms	Ethyl (1-{[3-(trifluoromethyl)phenyl]carbonyl}-4-piperidinylidene)acetate; 1-[3-(Trifluoromethyl)benzoyl]-4-(ethoxycarbonylmethylene)piperidine; Ethyl 2-(1-(3-(trifluoromethyl)benzoyl)piperidin-4-ylidene)acetate; 4-(Ethoxycarbonylmethylene)-1-[3-(trifluoromethyl)benzoyl]piperidine; 439095-20-2; Ethyl 2-(1-(3-(trifluoromethyl)benzoyl)-4-piperidinylidene)acetate
EINECS	Contact for details

Quality Control

Our Ethyl 2-(1-[3-(Trifluoromethyl)Benzoyl]-4-Piperidinylidene)Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.