Description

Benzenesulfonamide, 2-Fluoro-5-Methyl- (9Ci) is a specialized fluorinated aromatic sulfonamide derivative, identified by CAS NO 438539-71-0. This compound serves as a versatile and critical pharmaceutical intermediate and organic synthesis building block, prized for its unique chemical reactivity imparted by the fluorine substituent. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and pesticides, leveraging the bioactivity of the sulfonamide and fluorine groups.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers, liquid crystals, and advanced organic electronic materials.
• Chemical Biology & Proteomics: Acts as a scaffold or probe in the design of enzyme inhibitors and molecular tools for studying biological pathways.
• Organic Synthesis Reagent: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution reactions due to its reactive halogen and sulfonamide functionalities.
• Dye & Pigment Intermediate: Potential precursor in the manufacture of specialized dyes and colorants requiring sulfonamide and fluorine substituents for stability and hue.

Basic Information

Product Name	Benzenesulfonamide, 2-Fluoro-5-Methyl- (9Ci)
CAS No.	438539-71-0
Molecular Formula	C7H8FNO2S
Molecular Weight	189.21 g/mol
Synonyms	2-Fluoro-5-methylbenzenesulfonamide; 2-Fluoro-5-methylbenzene-1-sulfonamide; 5-Methyl-2-fluorobenzenesulfonamide; 1-Fluoro-4-methyl-3-sulfamoylbenzene; 3-Fluoro-6-methylbenzenesulfonamide; 2-Fluoro-5-methylphenylsulfonamide; Benzenesulfonamide, 2-fluoro-5-methyl-
EINECS	Contact for details

Quality Control

Our production of Benzenesulfonamide, 2-Fluoro-5-Methyl- (9Ci) adheres to stringent ISO 9001 quality management principles. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. For customers with specific regulatory needs, we can support documentation for REACH compliance and other global chemical inventories.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed immediately after use to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.