Description

3-(4-Iodo-Phenoxymethyl)-4-Methoxy-Benzaldehyde is a high-purity, multi-functional aromatic aldehyde building block designed for advanced organic synthesis. This compound is valued for its unique molecular architecture, which incorporates both an aldehyde group and an iodophenoxy moiety, enabling precise chemical modifications. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel active ingredients and functional intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly for oncology and CNS-targeted therapies.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and plant growth regulators requiring specific halogenated aromatic structures.
• Liquid Crystal & OLED Materials: Serves as a building block for creating advanced organic electronic materials due to its rigid, substituted benzaldehyde core.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Heck couplings.
• Chemical Biology Probes: Utilized in synthesizing molecular probes and tags for studying biological processes and protein interactions.
• Polymer & Resin Modification: Acts as a functional monomer or cross-linking agent for specialty polymers with tailored thermal and optical properties.

Basic Information

Product Name	3-(4-Iodo-Phenoxymethyl)-4-Methoxy-Benzaldehyde
CAS No.	438221-75-1
Molecular Formula	C15H13IO3
Molecular Weight	368.17 g/mol
Synonyms	4-Methoxy-3-[(4-iodophenoxy)methyl]benzaldehyde; 3-[(4-Iodophenoxy)methyl]-4-methoxybenzaldehyde; 4-Methoxy-3-(4-iodophenoxymethyl)benzaldehyde; Benzaldehyde, 3-[(4-iodophenoxy)methyl]-4-methoxy-; 438221-75-1; 3-(4-Iodophenoxymethyl)-4-methoxybenzaldehyde; 4-Methoxy-3-(4-iodo-phenoxymethyl)-benzaldehyde
EINECS	Contact for details

Quality Control

Every batch of 3-(4-Iodo-Phenoxymethyl)-4-Methoxy-Benzaldehyde is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our standard research-grade material typically meets a purity specification of ≥97% (HPLC). A detailed Certificate of Analysis (COA) is provided with each shipment, documenting results from HPLC, NMR, and IR spectroscopy. We support custom synthesis to meet specific purity requirements (e.g., ≥98% or ≥99%) for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.