Description

2-Pyrrolidinone,5-Ethyl-3-[3-(Trimethylsilyl)Propyl]-,(3R,5S)-Rel-(9Ci) is a high-purity, chiral pyrrolidinone derivative featuring a trimethylsilylpropyl side chain. This compound serves as a valuable advanced pharmaceutical intermediate (API) and a versatile building block in sophisticated organic synthesis. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.
• Agrochemical Synthesis: Used as a building block for developing new generation pesticides and herbicides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Serves as a precursor for silicon-containing polymers and advanced functional materials with tailored properties.
• Organic Synthesis Building Block: Utilized in multi-step synthetic routes to construct complex nitrogen and silicon-containing heterocycles.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development, validation, and quality control in regulated environments.

Basic Information

Product Name	2-Pyrrolidinone,5-Ethyl-3-[3-(Trimethylsilyl)Propyl]-,(3R,5S)-Rel-(9Ci)
CAS No.	437755-09-4
Molecular Formula	C12H25NOSi
Molecular Weight	227.42 g/mol
Synonyms	(3R,5S)-5-Ethyl-3-(3-(trimethylsilyl)propyl)pyrrolidin-2-one; rel-(3R,5S)-5-Ethyl-3-[3-(trimethylsilyl)propyl]-2-pyrrolidinone; 5-Ethyl-3-(3-trimethylsilylpropyl)pyrrolidin-2-one; (3R,5S)-rel-5-Ethyl-3-(3-(trimethylsilyl)propyl)-2-pyrrolidinone; 2-Pyrrolidinone, 5-ethyl-3-[3-(trimethylsilyl)propyl]-, (3R,5S)-rel-; Chiral Silylated Pyrrolidinone Derivative
EINECS	Contact for details

Quality Control

Every batch of this high-value intermediate is produced and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, Chiral HPLC, and NMR to ensure identity, purity, and enantiomeric excess meet exacting customer specifications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment. Our commitment to cGMP principles ensures traceability and consistency for critical pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.