Description

2-(3,5-Dimethylphenyl)-1,3,2-Dioxaborinane CAS NO 436853-63-3 is a high-purity, cyclic boronic ester derivative, a crucial protected boronic acid intermediate in modern synthetic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality building blocks for drug discovery, ligand synthesis, and organic electronic material development.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing biaryl motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides requiring specific aryl-aryl couplings.
• Material Science: Precursor for organic light-emitting diodes (OLEDs), organic photovoltaics (OPVs), and other electronic materials where controlled conjugation is critical.
• Catalyst & Ligand Development: Serves as a starting material for synthesizing sophisticated ligands used in asymmetric catalysis and transition metal complexes.
• Chemical Research: A versatile reagent in academic and industrial R&D for exploring new carbon-carbon bond-forming methodologies and creating compound libraries.
• Fine Chemical Production: Employed in the multi-step synthesis of complex fragrance, flavor, and specialty chemical compounds.

Basic Information

Product Name	2-(3,5-Dimethylphenyl)-1,3,2-Dioxaborinane
CAS No.	436853-63-3
Molecular Formula	C12H15BO2
Molecular Weight	202.06 g/mol
Synonyms	3,5-Dimethylbenzeneboronic acid 1,3-propanediol cyclic ester; 2-(3,5-Dimethylphenyl)-1,3,2-dioxaborinane; 3,5-Dimethylphenyl-1,3,2-dioxaborinane; (3,5-Dimethylphenyl)-1,3,2-dioxaborinane; 1,3-Propanediol cyclic ester with 3,5-dimethylbenzeneboronic acid; 3,5-Dimethylphenylboronic acid 1,3-propanediol ester; 436853-63-3
EINECS	Contact for details

Quality Control

Every batch of 2-(3,5-Dimethylphenyl)-1,3,2-Dioxaborinane is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high standards required for sensitive synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments. Our quality commitment supports compliance in cGMP, ISO, and other relevant regulatory frameworks for our global clientele.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term stability and to prevent hydrolysis. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.